ARA-290 is a variant of erythropoietin which has been shown to decrease inflammatory pathways through paracrine signaling and the innate repair receptors. Research has shown ARA-290 to help reduce HbA1c, improve cholesterol, modulate peripheral neuropathies and general neuropathic pain and stimulates wound repair.
AOD-9604 is a modified version of the hGH fragment 176-191 peptide (contains a di-sulfide bridge) and thus a derivative of human growth hormone (hGH). Originally developed as a lipolytic (fat burning) compound, AOD-9604 has shown benefit in studies of heart disease, osteoarthritis/cartilage repair, and metabolic syndrome. AOD-9604 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis in animal studies.